Recalcitrant Pyoderma Gangrenosum Treated With Thalidomide
نویسندگان
چکیده
منابع مشابه
Recalcitrant pyoderma gangrenosum treated with parenteral iron sucrose therapy
CASE REPORT A 30-year-old woman with a history of Crohn’s disease presented to the clinic shortly after placement of a diverting ileostomy with peristomal purulence, ulceration, and erythema (Fig 1). Biopsy-proven PG was diagnosed, and she was started on prednisone and intralesional triamcinolone. Over the next 10 years, she was prescribed various combinations of cyclosporine, intralesional tri...
متن کاملAdalimumab Therapy for Recalcitrant Pyoderma Gangrenosum
OBJECTIVE To describe a patient with treatment-refractory pyoderma gangrenosum and the outcome of a novel therapeutic approach. METHODS Case report and review of the literature. RESULTS A patient with inflammatory bowel disease developed severe pyoderma gangrenosum while receiving treatment with the chimeric anti-TNF-alpha antibody infliximab. Despite subsequent trials of numerous immunosup...
متن کاملPyoderma gangrenosum in pregnancy successfully treated with infliximab and prednisone
PG: pyoderma gangrenosum TNF: tumor necrosis factor INTRODUCTION Pyoderma gangrenosum (PG) is a neutrophilic dermatosis with an important inflammatory component that usually presents as a nonhealing ulcer. This cutaneous disorder has been associated with several systemic conditions including inflammatory bowel disease. Treatment options for PG in pregnancy are limited. We present a case of pyod...
متن کاملPyoderma gangrenosum.
Pyoderma gangrenosum (PG) is an idiopathic, ulcerative, noninfective chronic inflammatory skin disorder of unknown etiology. It is associated with systemic medical illness in 50% of cases like inflammatory bowel disease, systemic arthritis, haematological diseases and malignancies. Characteristic lesions begin as pustule or vesiculopustule and progresses to an ulcer or deep erosion with violace...
متن کاملHidradenitis suppurativa and concomitant pyoderma gangrenosum treated With infliximab.
Pyoderma gangrenosum (PG) and hidradenitis suppurativa (HS) are rare chronic inflammatory dermatoses of unknown etiologies that often are refractory to conventional treatments. The therapeutic benefits of tumor necrosis factor a (TNF-α) inhibitors have been reported in patients with refractory PG or HS. The copresentation of these 2 diseases has previously been described in several cases in the...
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ژورنال
عنوان ژورنال: Mayo Clinic Proceedings
سال: 2000
ISSN: 0025-6196
DOI: 10.4065/75.8.842